Detection of Anti-Strongyloides Antibodies in the Serum of Liver Transplant Recipients: Need of Screening for This Neglected Helminthiasis.
Marcelo Andreetta CorralDirce Mary Correia Lima MeiselMichelle Soares Gomes GouvêaMário Guimarães PessôaDanilo OrtigosoDébora Raquel Benedita TerrabuioIdessania Nazareth da CostaFabiana Martins de PaulaRonaldo César Borges GryschekPublished in: Parasite immunology (2024)
Immunosuppressed patients, particularly transplant recipients, can develop severe strongyloidiasis. This study aimed to detect anti-Strongyloides IgG antibodies in a panel of sera from liver transplant patients. Two techniques were used: ELISA as the initial screening test and Western blotting as a confirmatory test. ELISA reactivity of 10.9% (32/294) was observed. The 40-30 kDa fraction was recognised in 93.7% (30/32) of the patients, resulting in a positivity rate of 10.2%. These data highlight the importance of serological screening for Strongyloides stercoralis infection in liver transplant recipients.