Cesarean delivery is not associated with decreased at-birth fracture rates in osteogenesis imperfecta.
S BellurM JainD CuthbertsonD KrakowJ R ShapiroRobert D SteinerP A SmithMichael B BoberT HartJ KrischerM MullinsPeter H ByersMelanie G PepinM DurigovaF H GlorieuxF RauchV R SuttonB Leenull nullS C NagamaniPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)
Our study, the largest to analyze the effect of various factors on at-birth fracture rates in OI, shows that CD is not associated with decreased fracture rate. With the limitation that the fracture data were self-reported in this cohort, these results suggest that CD should be performed only for other maternal or fetal indications, not for the sole purpose of fracture prevention in OI.Genet Med 18 6, 570-576.