Utilization of Functionalized Metal-Organic Framework Nanoparticle as Targeted Drug Delivery System for Cancer Therapy.
Tran Anh VyVan Thuan LeVan Dat DoanGiang N L VoPublished in: Pharmaceutics (2023)
Cancer is a multifaceted disease that results from the complex interaction between genetic and environmental factors. Cancer is a mortal disease with the biggest clinical, societal, and economic burden. Research on better methods of the detection, diagnosis, and treatment of cancer is crucial. Recent advancements in material science have led to the development of metal-organic frameworks, also known as MOFs. MOFs have recently been established as promising and adaptable delivery platforms and target vehicles for cancer therapy. These MOFs have been constructed in a fashion that offers them the capability of drug release that is stimuli-responsive. This feature has the potential to be exploited for cancer therapy that is externally led. This review presents an in-depth summary of the research that has been conducted to date in the field of MOF-based nanoplatforms for cancer therapeutics.
Keyphrases
- metal organic framework
- cancer therapy
- papillary thyroid
- drug delivery
- squamous cell
- drug release
- squamous cell carcinoma
- lymph node metastasis
- machine learning
- public health
- gene expression
- wastewater treatment
- climate change
- deep learning
- genome wide
- small molecule
- childhood cancer
- risk assessment
- liquid chromatography
- molecularly imprinted