Kinin B1 Receptor Antagonism Prevents Acute Kidney Injury to Chronic Kidney Disease Transition in Renal Ischemia-Reperfusion by Increasing the M2 Macrophages Population in C57BL6J Mice.
Gabriel Rufino EstrelaRaisa Brito SantosAlexandre BuduAdriano Cleis de ArrudaJonatan Barrera-ChimalRonaldo Carvalho AraujoPublished in: Biomedicines (2023)
The B1R is pivotal to the evolution of AKI to CKD, and its antagonism shows potential as a therapeutic tool in the prevention of CKD following AKI.