Influence of a novel pH-cycling model using dental microcosm biofilm on the remineralizing efficacy of fluoride in early carious lesions.
Hae-Yun HwangHee Eun KimPublished in: Clinical oral investigations (2020)
The remineralizing efficacy of fluoride could be overestimated in the absence of dental biofilms. Therefore, for accurate evaluation of the clinical value of remineralizing agents, dental biofilms should be included in in vitro tests.