Urinary biomarkers of kidney tubule health and mortality in individuals with chronic kidney disease and diabetes mellitus.
George Vasquez-RiosRonit KatzEmily B LevitanAndrea N EdgintonChirag R ParikhPaul L KimmelJoseph V BonventreSushrut S WaikarSarah J SchraubenJason H GreenbergMark J SarnakJoachim H IxMichael G ShlipakOrlando M GutiérrezPublished in: Kidney360 (2023)
Among persons with diabetes and CKD, higher urine KIM-1 and YKL-40 were associated with a higher risk of all-cause mortality independently of established risk factors. Urine UMOD and MCP-1 were associated with cardiovascular- and cancer-related death, respectively.