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Clinical Implication of Toll-Like Receptors (TLR2 and TLR4) in Acute Myeloid Leukemia Patients.

Salah ArefAl Shaimaa Mansoura Abd ElmaksoudSherin Abd ElazizMohamed MabedMohamed Ayed
Published in: Asian Pacific journal of cancer prevention : APJCP (2020)
TLR2 Arg753Gln (AG; GG genotype) polymorphisms are associated with shortest OS and DFS. Moreover; significant association between TLR2 polymorphisms, TLR4 Arg753Gln polymorphisms and risk of severe infections in AML patients was documented.<br />.
Keyphrases
  • toll like receptor
  • inflammatory response
  • end stage renal disease
  • immune response
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • peritoneal dialysis
  • prognostic factors
  • nuclear factor
  • drug induced