Login / Signup

Aldosterone Effect on Cardiac Structure and Function.

Ekhlas Mahmoud Al-HashediFuad A Abdu
Published in: Current cardiology reviews (2024)
Aldosterone-mediated cardiovascular morbidity and mortality mainly result from cardiac structural and functional alterations. In different clinical settings, aldosterone can induce cardiac structural remodelling and dysfunction via several pathological mechanisms, including cardiac fibrosis, inflammation, and oxidative stress. Aldosterone antagonists could effectively decrease or reverse the detrimental aldosterone-mediated changes in the heart.
Keyphrases
  • oxidative stress
  • angiotensin ii
  • left ventricular
  • heart failure
  • signaling pathway
  • heat shock protein