Molecular matching for patients with haematological diseases expressing altered RHD-RHCE genotypes.

Bruno Ribeiro CruzThamy Caroline de Souza SilvaBianca de Souza CastroAkemi Kuroda ChibaElyse MoritzJosefina Pellegrini BragaMaria Stella FigueiredoJosé O Bordin

Published in: Vox sanguinis (2019)

We report the presence of clinically relevant RH genotypes in SCD and in non-SCD patients. In our admixed population, many patients carry variant RHCE alleles in heterozygosity with normal RHCE alleles. Thus, our results suggest that donors could be selected based on the normal RH allele.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes
kidney transplantation