LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson's Disease Cohort from Kazakhstan.

Rauan Kaiyrzhanov Akbota Aitkulova Chingiz Shashkin Nazira ZharkinbekovaMie RizigElena V Zholdybayeva Zharkyn Jarmukhanov Vadim Akhmetzhanov Gulnaz Kaishibayeva Talgat Khaibullin Altynay Karimova Serik Akshulakov Askhat Bralov Nurlan Kissamedenov Zhanar Seidinova Anjela Taskinbayeva Aliya Muratbaikyzy Henry Houlden

Published in: Parkinson's disease (2020)

We showed that East Asian LRRK variants could be found in Central Asian populations but their pathogenicity remains to be elucidated in larger PD cohorts.

Keyphrases

copy number
gene expression
cystic fibrosis
pseudomonas aeruginosa
genetic diversity