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Prognostic Biomarker-Based Identification of Drugs for Managing the Treatment of Endometrial Cancer.

Dilraj KaurChakit AroraGajendra Pal Singh Raghava
Published in: Molecular diagnosis & therapy (2021)
We identified potential immunotherapeutic agents based on prognostic gene signature: hexamethonium bromide and isoflupredone. Several novel candidate drugs were suggested, including human interferon-α-2b, paclitaxel, imiquimod, MESO-DAP1, and mifamurtide. These biomolecules and repurposed drugs may be utilised for prognosis and treatment for better survival.
Keyphrases
  • endometrial cancer
  • endothelial cells
  • genome wide
  • gene expression
  • risk assessment
  • dna methylation
  • bioinformatics analysis