A 5-Gene Signature Is Closely Related to Tumor Immune Microenvironment and Predicts the Prognosis of Patients with Non-Small Cell Lung Cancer.

Jia Li Huiyu WangZhaoyan LiChenyue ZhangChen-Xing ZhangCheng LiHaining YuHaiyong Wang

Published in: BioMed research international (2020)

The 5-gene signature is a powerful and independent predictor that could predict the prognosis of NSCLC patients. In addition, our gene signature is correlated with TIME parameters, such as DCs activated and MCs resting. Our findings suggest that the 5-gene signature closely related to TIME could predict the prognosis of NSCLC patients and provide some reference for immunotherapy.

Keyphrases

end stage renal disease
small cell lung cancer
copy number
ejection fraction
genome wide
newly diagnosed
chronic kidney disease
stem cells
prognostic factors
blood pressure
gene expression
heart rate
advanced non small cell lung cancer
heart rate variability
transcription factor