Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop.

Jonathan Alistair Cook Steven A JuliousWilliam SonesLisa V HampsonCatherine HewittJesse A BerlinDeborah AshbyRichard EmsleyDean A FergussonStephen J WaltersEdward Cf WilsonGraeme MacLennanNigel StallardJoanne C RothwellMartin BlandLouise BrownCraig R RamsayAndrew CookDavid ArmstrongDouglas AltmanLuke D Vale

Published in: Health technology assessment (Winchester, England) (2020)

Funded by the Medical Research Council (MRC) UK and the National Institute for Health Research as part of the MRC-National Institute for Health Research Methodology Research programme.

Keyphrases

quality improvement
healthcare
molecular dynamics
density functional theory
study protocol
molecular dynamics simulations
clinical trial