Exploring the role of ex vivo metabolism on blood and plasma measurements of oxytocin among women in the third stage of labour: a post-hoc study.

Victoria L OliverSarah SiedererAnthony CahnKatarzyna Gajewska-KnapikRachel A GibsonCleo GoodallCarl M J KirkpatrickJack MurrayTri-Hung NguyenIan SchneiderPete LambertMichelle P McIntoshSimon Parry

Published in: British journal of clinical pharmacology (2023)

Collection of blood from late-stage pregnant women into tubes containing EDTA inhibits oxytocinase effectively stabilises oxytocin, suggesting low concentrations of oxytocin after dose administration reflect rapid in vivo metabolism.

Keyphrases

pregnant women
pregnancy outcomes
polycystic ovary syndrome
type diabetes
metabolic syndrome
loop mediated isothermal amplification