Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma.
Mary Jane Lim-FatJ Bryan IorgulescuRifaquat RahmanVarun M BhaveAlona MuzikanskyEleanor WoodwardSydney WhorralMarie AllenMehdi TouatXiaomei LiGongwen XuJay PatelElizabeth R GerstnerJayashree Kalpathy-CramerGilbert YoussefUgonma N ChukwuekeJ Ricardo McFaline-FigueroaLakshmi NayakEudocia Quant LeeDavid A ReardonRameen BeroukhimRaymond Y HuangWenya Linda BiKeith L LigonPatrick Yung WenPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Genomic biomarkers based on functional variant analysis of a routine clinical panel may help identify AE in GBM, particularly seizures. Identifying these risk factors could improve the management of patients through better supportive care and consideration of prophylactic therapies.