Visual evoked and event-related brain potentials in HIV-infected adults: a longitudinal study over 2.5 years.
Jana SzanyiJan KremlacekZuzana KubovaMiroslav KubaPavel GebouskyJaroslav KaplaJuraj SzanyiFrantišek VítJana LangrovaPublished in: Documenta ophthalmologica. Advances in ophthalmology (2019)
Our aim was to evaluate whether antiretroviral treatment in HIV+ patients is sufficient to preserve brain visual function. The optic nerve and primary visual cortex function tested by the P-VEPs seem to be preserved. The prolongation of the M-VEPs suggests an individually detectable decline in CNS function, but these changes did not show a progression during the follow-up. From a longitudinal perspective, the trends in peak time prolongation of the 20' P-VEP, peripheral M-VEP, ERP and reaction time suggest a faster decline than that caused by aging in healthy populations, as previously described in a cross-sectional study.
Keyphrases
- hiv infected
- antiretroviral therapy
- human immunodeficiency virus
- optic nerve
- hiv positive
- hiv aids
- end stage renal disease
- ejection fraction
- newly diagnosed
- resting state
- white matter
- prognostic factors
- blood brain barrier
- physical activity
- optical coherence tomography
- hiv testing
- cerebral ischemia
- brain injury
- south africa
- patient reported