Pituitary Stalk Germ Cell Tumors: Retrospective Case Series and Literature Review.
Maria Eugenia SabatinoJuan Pablo PetitiYun XuPablo Anibal PérezPublished in: International journal of endocrinology (2022)
Isolated pituitary stalk lesions could be a signal of intracranial germ cell tumors, especially coexisting with diabetes insipidus, hypopituitarism, and a worse response to glucocorticoid therapy. Negative results of tumor markers and pathology could not exclude the diagnosis. Chemoradiotherapy is an effective therapy, leaving mild-t-moderate hypothalamus-pituitary dysfunction. This rare neuroimaging feature may be used as a factor to predict long-term neuroendocrine outcomes.