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Pituitary Stalk Germ Cell Tumors: Retrospective Case Series and Literature Review.

Maria Eugenia SabatinoJuan Pablo PetitiYun XuPablo Anibal Pérez
Published in: International journal of endocrinology (2022)
Isolated pituitary stalk lesions could be a signal of intracranial germ cell tumors, especially coexisting with diabetes insipidus, hypopituitarism, and a worse response to glucocorticoid therapy. Negative results of tumor markers and pathology could not exclude the diagnosis. Chemoradiotherapy is an effective therapy, leaving mild-t-moderate hypothalamus-pituitary dysfunction. This rare neuroimaging feature may be used as a factor to predict long-term neuroendocrine outcomes.
Keyphrases
  • germ cell
  • growth hormone
  • type diabetes
  • cardiovascular disease
  • machine learning
  • oxidative stress
  • glycemic control
  • high intensity
  • stem cells
  • adipose tissue
  • metabolic syndrome
  • mesenchymal stem cells
  • weight loss