Bone mesenchymal stem cells are recruited via CXCL8-CXCR2 and promote EMT through TGF-β signal pathways in oral squamous carcinoma.
Lin MengYueqi ZhaoWenhuan BuXing LiXinchen LiuDabo ZhouYumeng ChenShize ZhengQuan LinQilin LiuHongchen SunPublished in: Cell proliferation (2020)
Our results provide the molecular basis for BMSC recruitment into tumours, and how this process leads to tumour progression and leads us to develop a novel OSCC treatment target.