Drug Survival, Safety, and Effectiveness of Biologics in Older Patients with Psoriasis: A Comparison with Younger Patients-A BioCAPTURE Registry Study.
Elke L M Ter HaarSarah E ThomasJuul M P A van den ReekMarisol E OteroMarcellus D NjooPaul M OssenkoppeleE N KopSharon R P DodemontJ E M KörverAstrid L A KuijpersR J LindhoutRon A TupkerJohannes M MommersMaartje A M BerendsMarjolein I A KoetsierMarjolein de Bruin-WellerM B VischW P ArnoldPaula P van LümigM M KleinpenningSatish F K LubeekElke M G J de JongPublished in: Drugs & aging (2022)
This study in a substantial, well-defined, prospective cohort provides further support that the use of biologics in older patients seems well-tolerated and effective. Biologic discontinuation due to AEs did not occur more frequently in older patients. Older patients discontinued biologic treatment more often due to ineffectiveness, although no clear difference in PASI scores was observed. More real-world studies on physician- and patient-related factors in older patients are warranted.