Prevalence of strong anticholinergic use in residents with and without cognitive impairment and frailty: Analysis from 106 nursing homes in 12 Asia-Pacific and European countries.
Amanda J CrossEmanuele R VillaniAgathe D JadczakKaisu PitkäläShota HamadaMeng ZhaoMarta Gutiérrez-ValenciaUlla AaltoLaura A DowdLi LiShin J LiauRosa LiperotiNicolás Martínez-VelillaChoon Ean OoiGraziano OnderKate PetrieHanna M RoittoVictoria Roncal-BelzunceRiitta SaarelaNobuo SakataRenuka VisvanathanTiange G ZhangJ Simon BellPublished in: Archives of gerontology and geriatrics (2024)
One in six residents who were most frail and living with cognitive impairment used a strong anticholinergic. However, there was a 20-fold variation in prevalence across the 12 countries. Targeted deprescribing interventions may reduce potentially avoidable medication-harm.