Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue.

Alexandra Trinks Miha Milek Dieter BeuleJulie KlugeStefan Florian Christine Sers David Horst Markus Morkel Philip Bischoff

Published in: Cellular oncology (Dordrecht) (2024)

Our analysis highlights the potential of single-cell profiling in the analysis of retrospectively and prospectively collected archival pathology cohorts and increases the applicability in translational research.

Keyphrases

single cell
rna seq
high throughput
case report
label free
risk assessment
nucleic acid