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Associations of Enlarged Perivascular Spaces With Brain Lesions, Brain Age, and Clinical Outcomes in Chronic Traumatic Brain Injury.

Amelia J HicksBenjamin SinclairSandy ShultzWilliam PhamLisa C SilbertDaniel L SchwartzChristopher C RoweJennie Louise PonsfordMeng LawGershon Spitz
Published in: Neurology (2023)
TBI is associated with a greater burden of ePVS, especially when there have been bilateral brain lesions. ePVS was associated with reduced verbal memory performance. ePVS may indicate ongoing impairments in glymphatic system function in the chronic post-injury period.
Keyphrases
  • traumatic brain injury
  • resting state
  • white matter
  • working memory
  • functional connectivity
  • cerebral ischemia
  • multiple sclerosis
  • severe traumatic brain injury
  • brain injury
  • subarachnoid hemorrhage