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Exploring the Potential Molecular Mechanism of Sijunzi Decoction in the Treatment of Non-Segmental Vitiligo Based on Network Pharmacology and Molecular Docking.

Ziwei DuHepeng WangYang GaoShumao ZhengXiaoli KouGuo-Qiang SunJinxian SongJingfei DongGenhui Wang
Published in: Clinical, cosmetic and investigational dermatology (2023)
The results of this study indicate that quercetin, kaempferol, formononetin and naringenin in SJZD may play an important role in the treatment of non-segmental vitiligo by acting on AKT1, CASP3, PPARG, SIRT1, TNF and TP53 to regulate immune cell infiltration and multiple signaling pathways.
Keyphrases
  • molecular docking
  • signaling pathway
  • rheumatoid arthritis
  • cell proliferation
  • risk assessment
  • epithelial mesenchymal transition
  • ischemia reperfusion injury
  • human health
  • pi k akt
  • smoking cessation