REchallenge of NIVOlumab (RENIVO) or Nivolumab-Ipilimumab in Metastatic Renal Cell Carcinoma: An Ambispective Multicenter Study.
Charles VauchierEdouard AuclinPhilippe BarthélémyLucia Carril-AjuriaThomas RyckewaertDelphine BorchielliniZahra Castel-AjgalMostefa BennamounLuca CampedelAntoine Thiery-VuilleminElodie CoquanLaurence CrouzetJean-François BerdahChristine ChevreauRaffaele RattaAude FléchonFelix LefortLaurence AlbigesMarine Gross-GoupilYann-Alexandre VanoConstance ThibaultStephane Marie OudardPublished in: Journal of oncology (2022)
Rechallenge with nivolumab-based ICI has some efficacy in mRCC. We identified various prognostic factors in univariate analysis but only statistical trends in multivariate analysis. Our findings bring new evidence on ICI rechallenge and preliminary but unique data that may help clinicians to select patients who will benefit from this strategy.