Marine-Derived Penicillium purpurogenum Reduces Tumor Size and Ameliorates Inflammation in an Erlich Mice Model.

Amanda Mara TelesLeticia Prince Pereira PontesSulayne Janayna Araújo GuimarãesAna Luiza ButarelliGabriel Xavier SilvaFlavia Raquel Fernandes do NascimentoGeusa Felipa de Barros BezerraCarla Junqueira Moragas-TellisRui Miguel Gil da CostaMarcos Antonio Custódio Neto da SilvaFernando Almeida-SouzaKátia da Silva CalabreseMaria do Desterro Soares Brandão NascimentoMaria do Desterro Soares Brandão Nascimento

Published in: Marine drugs (2020)

These results indicate that P. purpurogenum exhibits immunomodulatory and antitumor properties in vivo. Thus, fungal fermentation is a valid biotechnological approach to the production of antitumor agents.

Keyphrases

oxidative stress
high fat diet induced
mouse model
saccharomyces cerevisiae
skeletal muscle