X chromosome inactivation skewing is common in advanced carotid atherosclerotic lesions in females and predicts secondary peripheral artery events.
Michele F BuonoErnest Diez BenaventeMark DanielsBarend M MolJoost M MekkeGert J de BorstDominique P V de KleijnSander W van der LaanGerard PasterkampCharlotte Onland-MoretMichal MokryHester M den RuijterPublished in: Biology of sex differences (2023)
XCI skewing is common in carotid plaques of females and is predictive for the occurrence of peripheral artery events within 3 years after carotid endarterectomy.