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Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway.

Hoang Tam Nguyen ThaiThuy-Vy NguyenThuy-Duong Ho-Huynh
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
These results suggested DNA damaging effect and ATR-CHK1-mediated cell cycle arrest of THMGT on MCF-7 cells resulting in apoptosis induction.
Keyphrases
  • cell cycle arrest
  • pi k akt
  • cell death
  • signaling pathway
  • dna damage
  • dna damage response
  • induced apoptosis
  • cell proliferation
  • oxidative stress
  • breast cancer cells
  • epithelial mesenchymal transition
  • cell free