Association between changes in oestradiol and follicle-stimulating hormone levels during the menopausal transition and risk of diabetes.
Sung Kyun ParkS D HarlowH ZhengC Karvonen-GutierrezR C ThurstonK RuppertI JanssenJ F RandolphPublished in: Diabetic medicine : a journal of the British Diabetic Association (2017)
Lower pre-menopausal oestradiol levels and a slower rate of follicle-stimulating hormone change during the early transition were associated with higher risk of developing diabetes. Given that obesity plays an important role in diabetes risk and in the levels and changes in oestradiol and follicle-stimulating hormone over the menopausal transition, weight control in earlier mid-life is important to prevent future diabetes development.