Subclinical affective and cognitive fluctuations in Parkinson's disease: a randomized double-blind double-dummy study of Oral vs. Intrajejunal Levodopa.

Jaime KulisevskyHelena Bejr-KasemSaul Martinez-HortaAndrea Horta-BarbaBerta Pascual-SedanoAntonia CampolongoJuan Marín-LahozIgnacio Aracil-BolañosJesús Pérez-PérezCristina Izquierdo-BarrionuevoOriol de FàbreguesVictor PuenteAne Crespo-CuevasMatilde CalopaJavier Pagonabarraga

Published in: Journal of neurology (2020)

Our sample of advanced PD patients exhibited moderate but significant non-motor fluctuations. LCIG was associated with a more favorable profile of acute affective and cognitive fluctuations that was particularly expressed at the first part of the infusion curve.

Keyphrases

bipolar disorder
ejection fraction
end stage renal disease
newly diagnosed
double blind
liver failure
low dose
prognostic factors
parkinson disease
high intensity
deep brain stimulation
drug induced
mass spectrometry
high resolution
phase iii
acute respiratory distress syndrome
mechanical ventilation