Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies.
Ines Pires daSilvaIsabella C Glitza OlivaLauren E HayduRomany JohnpullePatricia D BanksGeorge D GrassSimone M A GoldingerJessica L SmithAshlyn S EverettPeter KoelblingerRachel Roberts-ThomsonMichael MillwardVictoria G AtkinsonAlexander GuminskiRony KapoorRobert M ConryMatteo S CarlinoWei WangMark J ShackletonZeynep ErogluSerigne N LôAngela M HongGeorgina V LongDouglas B JohnsonAlexander M MenziesPublished in: Pigment cell & melanoma research (2019)
Radionecrosis is a significant toxicity in longer-term melanoma survivors with MBM treated with anti-PD-1 and radiotherapy. Identification of those at risk of radionecrosis who may avoid radiotherapy is required.