Development of a Fully Automated Desktop Analyzer and Ultrahigh Sensitivity Digital Immunoassay for SARS-CoV-2 Nucleocapsid Antigen Detection.
Ryotaro ChibaKei MiyakawaKotaro AokiTakamitsu J MorikawaYoshiki MoriizumiTakuma DegawaYoshiyuki AraiOsamu SegawaKengo TanakaHideji TajimaSusumu AraiHisatoshi YoshinagaRyohei TsukadaAkira TaniHaruhito FujiAkinobu SatoYoshikazu IshiiKazuhiro TatedaAkihide RyoToru YoshimuraPublished in: Biomedicines (2022)
Our d-IA system, which includes a novel fully automated desktop analyzer, enabled detection of the SARS-CoV-2 N-protein with a comparable sensitivity to RT-PCR within 30 min. Thus, d-IA shows potential for SARS-CoV-2 detection across multiple diagnostic centers including small clinics, hospitals, airport quarantines, and clinical laboratories.