Login / Signup

Dynamic updating of clinical survival prediction models in a changing environment.

Kamaryn T TannerRuth H KeoghCarol A C CouplandJulia Hippisley-CoxKarla Diaz-Ordaz
Published in: Diagnostic and prognostic research (2023)
We found that a dynamic updating process outperformed one-time discrete updating in the simulations. Bayesian updating offered good performance overall, even in scenarios with new predictors and few events. Intercept recalibration was effective in scenarios with smaller sample size and changing baseline hazard. Refitting performance depended on sample size and produced abrupt changes in hazard ratio estimates between periods.
Keyphrases
  • working memory
  • climate change
  • molecular dynamics
  • monte carlo