WGS of a cluster of MDR Shigella sonnei utilizing Oxford Nanopore R10.4.1 long-read sequencing.

Gordon RitchieSamuel D ChorltonNancy MaticJennifer BilawkaLeah GowlandVictor LeungAleksandra StefanovicMarc G RomneyChristopher F Lowe

Published in: The Journal of antimicrobial chemotherapy (2023)

WGS with R10.4.1 enabled rapid sequencing and identification of an MDR S. sonnei community cluster. Genetic predictors of AMR were concordant with phenotypic antimicrobial susceptibility testing.

Keyphrases

multidrug resistant
single molecule
single cell
healthcare
mental health
copy number
loop mediated isothermal amplification