IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C.

Benjamin KrämerClaudia FinnemannBeatriz SastrePhilipp LutzAndreas GlässnerFranziska WolterFelix GoeserPavlos KokordelisDominik KaczmarekHans-Dieter NischalkeChristian P StrassburgUlrich SpenglerJacob Nattermann

Published in: PloS one (2016)

Our data indicate that monocytes from carriers of an IL-28B T/T genotype display a reduced ability to stimulate NK cell activity and, thus, provide a link between IL-28B genotype and NK functions.

Keyphrases

nk cells
dendritic cells
peripheral blood
endothelial cells
diabetic rats
electronic health record
big data
drug induced
oxidative stress
machine learning