Cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells.

Jailson Rodrigues Dos SantosLarissa de Sousa SoaresBruno Moreira SoaresMarlene de Gomes FariasVictor Alves de OliveiraNatan Antônio Batista de SousaHelber Alves NegreirosFelipe Cavalcanti Carneiro da SilvaAna Paula PeronAna Carolina Landim PachecoMárcia Maria Mendes MarquesJuan Carlos Ramos GonçalvesRaquel Carvalho MontenegroMuhammad Torequl IslamJavad Sharifi RadMohammad S MubarakAna Amélia Carvalho de Melo CavalcanteJoão Marcelo de Castro E Sousa

Published in: BMC pharmacology & toxicology (2022)

Taken together, TRZ exerted toxicogenic effects on the test systems. Therefore, it may be harmful to health, especially its prolonged use may trigger carcinogenesis.

Keyphrases

induced apoptosis
healthcare
public health
cell cycle arrest
mental health
human health
endoplasmic reticulum stress
oxidative stress
cell death
risk assessment
climate change