Stereodivergent Mannosylation Using 2- O-( ortho-Tosylamido)benzyl Group.

We report a novel strategy for obtaining both anomers from a single mannosyl donor equipped with a C2- o-TsNHbenzyl ether (2- O-TAB) by switching reaction conditions. In particular, the formation of various β-mannosides was achieved with high selectivity by using a mannosyl phosphite in the presence of ZnI2.