Short-term resistance exercise inhibits neuroinflammation and attenuates neuropathological changes in 3xTg Alzheimer's disease mice.
Yan LiuJohn Man Tak ChuTim YanYan ZhangYing ChenRaymond Chuen Chung ChangGordon Tin Chun WongPublished in: Journal of neuroinflammation (2020)
Short-term resistance training improved cognitive function in 3xTg mice, and conferred beneficial effects on neuroinflammation, amyloid and tau pathology, as well as synaptic plasticity. Resistance training may represent an alternative exercise strategy for delaying disease progression in Alzheimer's disease.
Keyphrases
- resistance training
- high intensity
- body composition
- high fat diet induced
- lipopolysaccharide induced
- traumatic brain injury
- cognitive decline
- lps induced
- cognitive impairment
- type diabetes
- inflammatory response
- cerebral ischemia
- cerebrospinal fluid
- wild type
- insulin resistance
- metabolic syndrome
- blood brain barrier