Cardiovascular and renal effects of SGLT2 inhibitor initiation in acute heart failure: a meta-analysis of randomized controlled trials.
Pedro Emanuel de Paula CarvalhoThiago M A VeigaAna C Simões E SilvaDouglas M GewehrCaroline S DagostinAmanda FernandesGuilherme NasiRhanderson CardosoPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2023)
SGLT2i addition to conventional diuretic therapy reduced all-cause death, readmissions for HF, and the composite of cardiovascular death or readmissions for HF. Moreover, SGLT2i was associated with a higher volume of diuresis with a lower dose of loop diuretics.