Assessment of tumour-associated necrosis provides prognostic information additional to World Health Organization/International Society of Urological Pathology grading for clear cell renal cell carcinoma.
Julien DagherBrett DelahuntNathalie Rioux-LeclercqLars EgevadGeoff CoughlinNigel DunglisonTroy GianduzzoBoon KuaGreg MaloneBen MartinJohn PrestonMorgan PokornySimon WoodHemamali SamaratungaPublished in: Histopathology (2018)
Tumour-associated necrosis is an important prognostic factor for clear cell RCC, independently of WHO/ISUP grade. This supports the suggestion that TAN could be incorporated into tumour grading criteria.