Oncogenic alterations in KIR3DL1 in cutaneous acral CD8+ lymphoproliferative disorder.

Marion WobseSilke AppenzellerSabine RothClaudia SiedelMatthias GoebelerEva GeissingerAndreas RosenwaldKatja Maurus

Published in: The British journal of dermatology (2024)

Alterations of KIR3DL1 gene may be of pathogenetic relevance for acral CD8+ TLPD. Loss of KIR3DL1 protein expression may support the diagnosis of this indolent lymphoma entity, albeit not being a subtype-specific discriminative feature.

Keyphrases

epstein barr virus
diffuse large b cell lymphoma
nk cells
transcription factor
deep learning
genome wide
copy number
genome wide identification