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Disseminated gonococcal infection in a Japanese man with complement 7 deficiency with compound heterozygous variants: A case report.

Misaki KageyamaHideharu HagiyaYasutaka UedaKatsuki OhtaniYasuo FukumoriNorimitsu InoueNobutaka WakamiyaNanoka YonedaKeigo KimuraMotonori NagasawaFutoshi NakagamiIsao NishiKen SugimotoHiromi Rakugi
Published in: Medicine (2021)
DGI is a rare sexually-transmitted infection that potentially induces systemic complications. Complement immunity usually defeats N. gonorrhoeae and prevents the organism from causing DGI. This case highlighted the importance of suspecting a complement deficiency when a person develops DGI.
Keyphrases
  • early onset
  • replacement therapy
  • mouse model
  • gene expression
  • dna methylation
  • drug induced