Can cannabidiol have an analgesic effect?
Bartłomiej KuleszaMarek MazurekJacek KurzepaPublished in: Fundamental & clinical pharmacology (2023)
The analgesic effect of CBD is complex and still being researched. CBD models the perception of pain by acting on G protein-coupled receptors. Another group of receptors that CBD acts on are serotonergic receptors. The effect of CBD on an enzyme of potential importance in the production of inflammatory factors such as cyclooxygenases and lipoxygenases has also been confirmed. The presented potential mechanisms of CBD's analgesic effect are currently being extensively studied.