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The constitutive differential transcriptome of a brain circuit for vocal learning.

Peter V LovellNicole A HuizingaSamantha R FriedrichMorgan WirthlinClaudio V Mello
Published in: BMC genomics (2018)
Our study represents one of the most comprehensive molecular characterizations of a brain circuit that evolved to facilitate a learned behavior in a vertebrate. The data provide novel insights into possible molecular determinants of the functional properties of the song control circuitry. It also provides lists of compelling targets for pharmacological and genetic manipulations to elucidate the molecular regulation of song behavior and vocal learning.
Keyphrases
  • resting state
  • white matter
  • gene expression
  • single molecule
  • functional connectivity
  • electronic health record
  • machine learning
  • big data
  • blood brain barrier
  • data analysis