Real-life assessment of standardized contrast-enhanced ultrasound (CEUS) and CEUS algorithms (CEUS LI-RADS®/ESCULAP) in hepatic nodules in cirrhotic patients-a prospective multicenter study.

D StrobelE-M JungM ZieschM PraktiknjoA LinkC F DietrichC KlingerM SchultheißD JesperBarbara Schellhaas

Published in: European radiology (2021)

• Contrast-enhanced ultrasound (CEUS) has a high diagnostic accuracy for the non-invasive diagnosis of hepatocellular carcinoma (HCC) in cirrhosis. • The CEUS algorithm ESCULAP (Erlanger Synopsis for Contrast-enhanced Ultrasound for Liver lesion Assessment in Patients at risk) showed the highest sensitivity, whereas the CEUS LI-RADS® (Contrast-Enhanced UltraSound Liver Imaging Reporting and Data System) algorithm yielded the highest specificity. • A standardized CEUS examination procedure with an additional examination point in the late phase, after 4-6 min in lesions with no washout after 3 min, is vital.

Keyphrases

contrast enhanced ultrasound
end stage renal disease
machine learning
chronic kidney disease
newly diagnosed
deep learning
prognostic factors
patient reported outcomes
mass spectrometry
ion batteries
structural basis