Sex-related differences in patients presenting with heart failure-related cardiogenic shock.
Jonas SundermeyerCaroline KellnerBenedikt N BeerLisa BeschAngela DettlingLetizia Fausta BertoldiStefan BlankenbergJeroen DauwZouhir DindaneDennis EcknerIngo EitelTobias GrafPatrick HornJoanna Jozwiak-NozdrzykowskaPaulus KirchhofStefan KlugeAxel LinkeUlf LandmesserPeter LuedikeEnzo LüsebrinkNicolas MajunkeNorman MangnerOctavian ManiucSven Möbius-WinklerPeter NordbeckMartin OrbanFederico PappalardoMatthias PauschingerMichal PazdernikAlastair ProudfootMatthew KelhamTienush RassafClemens SchererPaul Christian SchulzeRobert H G SchwingerCarsten SkurkMarek SramkoGuido TavazziHolger ThieleLuca VillanovaNuccia MoriciEphraim B WinzerDirk WestermannBenedikt SchragePublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2024)
In this large HF-CS registry, sex disparities in risk factors and clinical presentation were observed. Despite these differences, the use of treatments was comparable, and both sexes exhibited similarly high mortality rates. Further research is necessary to evaluate if sex-tailored treatment, accounting for the differences in cardiovascular risk factors and clinical presentation, might improve outcomes in HF-CS.