Resiquimod-Mediated Activation of Plasmacytoid Dendritic Cells Is Amplified in Multiple Sclerosis.
Marta CorsettiGabriella RuoccoSerena RuggieriClaudio GasperiniLuca BattistiniElisabetta VolpePublished in: International journal of molecular sciences (2019)
Overall, these results indicate that activation of pDCs is enhanced in MS, likely due to a latent viral infection, and that costimulatory molecules expressed on pDCs could mediate a protective response against the viral trigger of autoimmunity.