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Resiquimod-Mediated Activation of Plasmacytoid Dendritic Cells Is Amplified in Multiple Sclerosis.

Marta CorsettiGabriella RuoccoSerena RuggieriClaudio GasperiniLuca BattistiniElisabetta Volpe
Published in: International journal of molecular sciences (2019)
Overall, these results indicate that activation of pDCs is enhanced in MS, likely due to a latent viral infection, and that costimulatory molecules expressed on pDCs could mediate a protective response against the viral trigger of autoimmunity.
Keyphrases
  • dendritic cells
  • multiple sclerosis
  • regulatory t cells
  • immune response
  • sars cov
  • ms ms
  • white matter