Epithelial deletion of the glucocorticoid receptor (Nr3c1) protects the mouse intestine against experimental inflammation.
María Arredondo-AmadorCarlos J ArandaBorja OcónRaquel GonzálezOlga Martínez-AugustinFermín Sánchez de MedinaPublished in: British journal of pharmacology (2021)
The intestinal epithelial glucocorticoid receptor has deleterious effects in experimental colitis induced by DSS, probably related to inhibition of epithelial proliferative responses leading to impaired wound healing and reduced endogenous corticosterone production.
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