Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project.

Andrea M IsidoriElisa GiannettaRiccardo PofiMary A VenneriDaniele GianfrilliFederica CampoloClaudio M MastroianniAndrea LenziGabriella d'Ettorre

Published in: Andrology (2020)

If the ongoing trials presented herein should provide positive findings, the low cost, wide availability and temperature stability of PDE5 inhibitors could make them a major resource to combat COVID-19 in developing countries.

Keyphrases

low cost
coronavirus disease
sars cov
nitric oxide
quality improvement
cancer therapy
protein kinase
drug delivery