Missing Causality and Heritability of Autoimmune Hepatitis.

Published in: Digestive diseases and sciences (2022)

Autoimmune hepatitis has a missing causality that might be explained by epigenetic changes induced by environmental factors and a missing heritability that might reflect epistatic gene interactions or transgenerational transmission of acquired epigenetic marks. These unassessed or under-evaluated areas warrant investigation.

Keyphrases

dna methylation
gene expression
multiple sclerosis
adverse drug
genome wide
drug induced
copy number
transcription factor
genome wide identification
genome wide association