Group B Streptococcus capsular serotype alters vaginal colonization fitness.
Allison N DammannAnna B ChambyFrancisco J GonzalezMolly E SharpKarina FloresIfrah ShahiSophia DongasThomas A HoovenAdam J RatnerPublished in: The Journal of infectious diseases (2021)
Specific capsule types may provide an advantage in GBS vaginal colonization in vivo. However, success of certain GBS lineages, including CC17, likely involves both capsule and non-capsule genetic elements. Capsule switching in GBS, a potential outcome of conjugate vaccine programs, may alter colonization fitness or pathogenesis.